The side effects of many medicines can be so broad it may difficult to list everything here. However, there are some common meds that are known to sometimes cause ED. Most anti-hypertensive meds will supportive of reversing ED symptoms, however, lisinopril is one anti-hypertensive known to sometimes cause ED. The mechanism is not clear here, although lisinopril is known to sometimes reduce free testosterone so this could be the reason. Anti-depressant drugs of all types are the meds that most often are known to both reduce sex drive and cause ED issues. Welbutrin, sertraline, fluoxetine, and citalopram all have shown some evidence of causing ED. Coincidentally citalopram in small doses is sometimes used as a medication to treat premature ejaculation.